New Mechanisms Elicited with Ketamine in Treatment-Resistant Depression

Ronald S. Duman, PhD, Elizabeth Mears, Ph.D., and House Jameson, Ph.D., Professor of Psychiatry and Professor of Neurobiology and of Pharmacology at Yale School of Medicine, discuss advances in the treatment of depression. (April 2011)

Our Patients Say…

Darkness Lifted

Having suffered from medication resistant Major Depressive Disorder, Anxiety and PTSD for most of my life. I found unbelievable life changing results from Dr. Calabrese through Ketamine infusions. The only way I can explain the results of Ketamine is to make the comparison to the movie The Wizard of Oz. In the beginning everything is dark, gloomy and depressing. Immediately after my Ketamine treatment it’s like after the door is open to OZ everything bright, clear and happy. In a day I cared about things I hadn’t, wanted to do things again and had energy and focus. I can’t thank Dr. Calabrese enough. She was kind, very knowledgeable and easy to talk to. Her staff was patient and friendly. Her facility was immaculately clean and welcoming.

Lisa P Bridgton, ME July 15, 2024

You Made a Significant Impact on My Life

Thank you! I am incredibly grateful for both of your medical expertise during this difficult time for me and my family. Dr Calabrese, I cannot express how relaxed and confident you make us feel when we talk with you. Every time we end a science-filled, informative conversation with you we breath a sigh of relief. Not to mention your innovative techniques with keto have likely made a significant contribution to my progress. Thank you for being a fantastic psychiatrist. Rachel, we've been blessed with your food and diet knowledge--it's helped us nail down this diet. Without your constant slew of advice, tips and tricks, recipes and simple encouragement, we likely would not be in the comfort we are in. Although there's still lots of difficulty, you both have made a significant impact on my life.

AA Disclaimer: Everyone's different, and your results may vary. Washington DC area February 10, 2024

Leap of Faith

I have been a patient with Doctor Calabrese for many years now. I have been through many different medication combinations to treat my symptoms. Throughout all of the trial and errors I remained hopeful that Dr. Calabrese would find the right combination of meds. She has!!! I feel better mentally now than I have since I have been with her. Unfortunately, throughout my years of being on medication I have put on a great deal amount of weight. Over 150 pounds to be exact. Recently Dr. Calabrese explained to me about a new addition to her practice, the metabolic psychiatry program. I was a little skeptical at first because I have tried and failed so many diets, more than I can even tell you. I was thinking that this would be another failure and I was unsure that I wanted to pursue it. I not only would be putting all Continue Reading

Lisa P. Disclaimer: Everyone’s different, and your results may vary. Windsor, CT January 29, 2023

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Lori Calabrese, MD

New Mechanisms Elicited with Ketamine in Treatment-Resistant Depression

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