Suicidal Thoughts

Revitalize Psychiatry: Disrupt – Include – Engage – Innovate !! – The APA 2019 Conference

Disrupt, Include, Engage, Innovate was the theme of the 2019 APA Conference.

I just returned from the American Psychiatric Association’s 2019 Conference in San Francisco. This is the 175th Anniversary of the APA, and look how far we’ve come. The theme this year was: Revitalize Psychiatry – Disrupt – Include – Engage – Innovate. and it certainly provided fodder toward those goals. It was an informative and […]

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Relieving Treatment-Resistant Depression By Treating Metabolic Deficiencies

Originally published in Brain & Behavior Magazine, July 2017 An important discovery has been made at the University of Pittsburgh. It raises the prospect that there may be an entirely new way of relieving major depression in people who repeatedly have failed to respond to existing treatments—people at elevated risk for suicide whose lives are often unrelentingly dark […]

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Treating Mood Disorders: Is the Key Hidden in the CSF?

No Wonder Treatment Resistance Has Been Such a Mystery! Clue: Look in the Cerebral Spinal Fluid! A man in his forties, Greg had never experienced life without depression. Treating mood disorders didn’t seem to be his psychiatrist’s forte. (Oh boy…) At least not in his case. Every accomplishment, every failure, struggled for expression beneath the […]

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Ketamine Restores Brain Circuitry Damaged by Depression – FAST

Ketamine restores brain circuitry to bring joy to depressed people.

In a world where things go wrong and people get sick, every once in awhile something comes along that makes things right again. I’m talking about something that’s so dramatic in its solutions we’re tempted to call it a “miracle.”  But we won’t. We’ll call it a game-changer. Because IV ketamine treatment is changing history. […]

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Behind the Buzz: How Ketamine Changes the Depressed Patient’s Brain

The anesthetic-cum-party drug restores the ability to make connections among brain cells. The Food and Drug Administration’s approval last month of a depression treatment based on ketamine generated headlines, in part, because the drug represents a completely new approach for dealing with a condition the World Health Organisation has labelled the leading cause of disability […]

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Cerebral Folate Deficiency and Its Impact on Treatment-Resistance

Man thinks alone on cold silent shore may have cerebral folate deficiency.

“If I see far, it’s that I stand on the shoulders of giants.” If you find yourself feeling alone and forgotten in your symptoms, feeling that there’s no one who really cares, please let me emphasize that there are hundreds, even thousands, of neuroscience researchers, medical doctors with PhDs, biochemists, psychopharmacologists, and psychiatrists who have […]

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Ketamine May Relieve Depression By Repairing Damaged Brain Circuits

Ketamine appears to restore faulty connections between brain cells, according to research performed in mice. The anesthetic ketamine can relieve depression in hours and keep it at bay for a week or more. Now scientists have found hints about how ketamine works in the brain. In mice, the drug appears to quickly improve the functioning […]

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Weekly Ketamine Infusions Show Initial, Repeated Depression Benefits

A new study shows that weekly ketamine infusions are associated with continued and maintained reductions in depressive symptoms among patients with treatment-resistant depression. The findings, which are considered novel among studies assessing ketamine administration for patients with treatment-resistant depression, evidence the promising role the controversial drug could play in psychiatric care. A team of investigators, led […]

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