News & Media

From Drug of Abuse to a Glimpse Into Depression

Date: May 18, 2016 Source: American Association of Pharmaceutical Scientists (AAPS) Summary: Ketamine, a synthetic analogue of PCP, has recently taken the spotlight as a novel, fast-acting antidepressant. However, experts say that more research on usage of ketamine as an antidepressant is needed.

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Ketamine Lifts Depression via a Byproduct of its Metabolism

Date: May 4, 2016 Source: NIH/National Institute of Mental Health Summary: A chemical byproduct, or metabolite, created as the body breaks down ketamine likely holds the secret to its rapid antidepressant action. This metabolite singularly reversed depression-like behaviors in mice without triggering any of the anesthetic, dissociative, or addictive side effects associated with ketamine. The […]

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