News & Media

No. 7 Medical Innovation for 2017: Ketamine for Treatment-Resistant Depression (Video)

Hope and Fast Treatment for the Severely Depressed. For one-third of U.S. patients with depression, standard medications aren’t enough. With nearly 43,000 suicides a year, the need for effective treatment looms large. In 2013, ketamine, a drug commonly used for anesthesia, was studied for its ability to inhibit nerve cells’ N-methyl-D-aspartate (NMDA) receptors. Within 24 […]

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Low-Dose Ketamine In Treating Depression: An Outsider’s Perception

connecticut ketamine

Mother and Healthcare Professional Discusses Her Child’s Experience with Low-Dose Ketamine for Treatment Resistant Depression As both a healthcare professional and a parent of a child who suffers from treatment resistant depression and anxiety, I have been quite attentive to the changes that arise in an individual after receiving low-dose ketamine. I thought it would […]

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Newsweek: Could Ketamine be the Ultimate Cure for Depression?

Ketamine, or “Special K” as it is commonly known, is a powerful anaesthetic that leaves the user feeling lifeless and physically detached from their senses. However, medical experts now believe the popular party drug could be the leading treatment for severe depression and suicidal thinking. According to the Washington Post, studies over the past decade […]

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Newsweek: Ketamine Restores Ability to Experience Pleasure in Depressed Patients within Minutes

There are many faces to depression: sadness, hopelessness, trouble sleeping, lack of motivation, an inability to experience pleasure. That last one has a medical name—anhedonia—and people experiencing it often no longer enjoy activities that used to bring happiness. Anhedonia is not found just in depression; it can be an important part of other disorders, including […]

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Ketamine Curbs Suicidal Ideation Independent of Antidepressant Effect

Key clinical point: Ketamine quickly reduces suicidal ideation even in patients whose depressive symptoms are unresponsive. Major finding: Ketamine infusions significantly reduced suicidal ideation even in patients whose treatment-resistant depression did not respond to the drug. Data source: This ongoing observational study included 27 patients with treatment-resistant depression who received seven intravenous infusions of ketamine […]

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What It’s Like to Have Your Severe Depression Treated With a Hallucinogenic Drug

Everyone’s depression is different, but Ted, a 40-year-old resident of Portland, Oregon, describes his as a “continuous dark veil — a foul, dark, awful perspective that informs every moment of your whole life.” He’d tried to treat it with antidepressants, therapy, visits to psychiatrists, “the whole nine,” but although the antidepressants kept him functional, they […]

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Street Drug ‘Special K’ May Offer New Hope For People With Treatment-Resistant Depression

A hallucinogenic drug known on the street as “Special K” offers new hope to those suffering from severe, treatment-resistant depression. Ketamine, which was originally developed in the 1960s as a milder version of PCP, already has a well-established medical use as a sedative or pain killer. But since 2000, small but high-quality studies have demonstrated […]

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Symptomatology and Predictors of Antidepressant Efficacy in Extended Responders to a Single Ketamine Infusion

Abstract BACKGROUND: Antidepressant response to a single sub-anesthetic dose infusion of the glutamatergic modulator ketamine is transient in most depressed patients; however, a minority continue to experience an extended response. This study examined depressive symptoms and potential clinical predictors of extended response to ketamine in subjects with mood disorders and found that a dissociative response […]

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