News & Media

The FDA approved a new ketamine depression drug — here’s what’s next

The newly approved drug, esketamine, is one half of the ketamine compound. By Angela Chen@chengela  Mar 11, 2019, 3:45pm EDTIllustration by Alex Castro/The Verge For years, ketamine clinics across the country have offered intravenous infusions as a fast-acting treatment for severe depression. But last week, the US Food and Drug Administration approved a version of ketamine, called esketamine, […]

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FDA approves new nasal spray medication for treatment-resistant depression; available only at a certified doctor’s office or clinic

For Immediate Release March 5, 2019 Release The U.S. Food and Drug Administration today approved Spravato (esketamine) nasal spray, in conjunction with an oral antidepressant, for the treatment of depression in adults who have tried other antidepressant medicines but have not benefited from them (treatment-resistant depression). Because of the risk of serious adverse outcomes resulting […]

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Johnson & Johnson’s nasal spray for depression wins FDA panel backing

(Reuters) – An advisory panel to the U.S. Food and Drug Administration on Tuesday voted in favor of Johnson & Johnson’s experimental nasal spray, which has a compound similar to often-abused ketamine, bringing the drug closer to approval. The panel voted 14-2 in favor of the drug esketamine, developed to treat major depression in patients […]

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Can We Stop Suicides?

By Moises Velasquez-Manoff –Contributing Opinion Writer It’s been way too long since there was a new class of drugs to treat depression. Ketamine might be the solution. In May of 2017, Louise decided that her life was just too difficult, so she’d end it. In the previous four years, three siblings and a half-sibling had died, […]

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Can a party drug stop the increasing rate of suicide?

Ketamine is showing promise in alleviating suicidal thoughts. DEREK BERES 03 December, 2018 The popular party drug has shown promise in stopping suicidal thoughts in a number of small clinical studies. First synthesized in 1962, the anesthetic was used to treat Vietnam War soldiers in the early seventies. Though the accompanying hallucinations are a roadblock to […]

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Trippy depression treatment? Hopes and hype for ketamine

By Lindsey Tanner | APOctober 31 at 12:14 PM CHICAGO — It was launched decades ago as an anesthetic for animals and people, became a potent battlefield pain reliever in Vietnam and morphed into the trippy club drug Special K. Now the chameleon drug ketamine is finding new life as an unapproved treatment for depression and suicidal behavior. […]

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Researchers identify effective ketamine dosage levels for patients with treatment-resistant depression

A study led by Massachusetts General Hospital (MGH) investigators identifies two subanesthetic dosage levels of the anesthetic drug ketamine that appear to provide significant symptom relief to patients with treatment-resistant depression. In the October 2018 issue of Molecular Psychiatry they describe finding that single intravenous doses of 0.5 mg/kg and 1.0 mg/kg were more effective than an […]

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As ketamine clinics spread, so do start-your-own-business courses, sparking concern

By MEGAN THIELKING @meggophone OCTOBER 11, 2018 As ketamine clinics pop up across the U.S. to offer experimental infusions for depression, anxiety, and a slew of other conditions, training programs to teach providers how to run these businesses have also started to appear. They promise to teach everyone from anesthesiologists to advanced practice nurses the ins and outs of […]

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Ketamine gives hope to patients with severe depression. But some clinics stray from the science and hype its benefits

Walk into Kalypso Wellness Centers in San Antonio, Texas, and you might be treated with one of five “proprietary blends” of ketamine. They’re not cheap — $495 per infusion — and not covered by insurance, but the company offers a “monthly” membership program to cut costs and advertises discounts for members of the military and first responders. Kalypso […]

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