Don’t you just hate it? Hate the drudgery and pain of fighting an illness that doesn’t respond to treatment? Granted, there are some illnesses that you can find remedies for, and recover. Maybe a steroid injection, or an antibiotic, and you start noticing improvement in a couple of days. But not all disorders are like […]
Bipolar Disorder
Articles About Bipolar Disorder from Lori Calabrese, MD | The Ketamine Blog
Serious and Complex Condition
Bipolar disorder’s symptoms demonstrate a complex brain and behavior disorder characterized first and foremost by severe mood swings. Secondly, it includes an inability to regulate your emotions and responses Because of that, you have times of extreme emotional lows we call bipolar depression, and times of extreme highs we call mania or hypomania. Therefore, sometimes you suffer through both at the same time.
It’s notable that each mood can last for months or weeks or days… or even hours before it swings just as severely to the other extreme.
Sadly. people with this disorder often face suicidal thoughts, or specific plans for ending their lives. In addition, they show impulsivity. The result of the combination of impulsivity and suicidal thoughts is a dangerous mixture, that far too often ends in fatality.
For this reason, this disorder reduces longevity by an average of 25% less than healthy persons.
These articles about bipolar disorder are available to you to help you understand this condition better, and hopefully to better understand the one who suffers with it.
Causes of Bipolar Disorder
While we don’t know exactly what causes bipolar disorder, we do know that a combination of genetics, environment, altered brain structure and chemistry all contribute.
For one thing, we know the amygdala and hippocampus play significant roles in this disorder. These structures in the brain help form new memories and process learning and emotions.
As a result, when the hippocampus and amygdala malfunction, the result can be a mixture of memories that store painful emotions that are so relentless that the sufferer finds it difficult to recover from hurts and traumatic events many years later, as well as to forgive someone who has hurt him.
These difficulties cause severe distress for the sufferer who finds it almost impossible to let go of traumatic memories and loss. Instead, he suffers the full pain of the memory each time it comes to mind.
Cheating Death
So, a damaged amygdala can lead to a lack of natural fear of danger. Furthermore, possibly linked to this is the pursuit of adrenalin-stimulating opportunities. A common trait in those with bipolar disorder, you tend to crave danger, thrills, and activities that “cheat death”… and other forms of high risk behavior. Since the amygdala consists of two parts – one on each side of the brain – if both are damaged it results in the sufferer’s inability to distinguish emotion response in the facial expressions of others. Consequently, this type of damage may be linked to autism.
Symptoms
Symptoms of bipolar disorder can include:
-mood swings
-difficulty regulating emotion
-intense outbursts
-rapid pressured speech
-hypersexuality
-high risk behavior
-visual and/or auditory hallucinations
-grandiosity
-delusions
-severe insomnia
-hypersomnia
-suicidal thoughts
-feelings of worthlessness
-hopelessness
-despair
-lack of energy or hyper-energy
-difficulty focusing or retaining information
-shame, low self-esteem and therefore sometimes a belief that one has low intelligence
Mixed States
Some people experience long periods of depression with negative beliefs about themselves, then long periods – or short periods – of mania or hypomania with all the more energized symptoms, including overconfidence and grandiosity. In addition, some people suffer from mixed states which is a mixture of both.
At the same time, this person may experience high energy, sleeplessness, racing thoughts, and rapid speech combined with irritability, rage, explosiveness, despair, and suicidal inclinations.
Types of Bipolar Disorder
Bipolar 1 – most intense and severe
Bipolar 2 – also can be severe, consists of longer periods of depression interrupted by hypomania, which is less intense than mania.
Cyclothymic Disorder – shorter periods of less intense depressive symptoms alternating with shorter periods of hypomanic feelings.
Fear of Harm Bipolar Disorder – begins in children and consists of acute fear of harming others and/or of being harmed.
Bipolar Disorder of each type is a serious disorder. Continue reading these articles about bipolar disorder to learn more.
IV Ketamine + Neuroplasticity = Relief, Relaxation, and Relishing Life
I could use some of that. We hear that all the time. Relief, relaxation and relishing your life can sound so far away … but it doesn’t have to be. As word gets out about IV ketamine treatment for depression and other psychiatric mood disorders, more and more studies are emerging. New information is surfacing […]
Ketamine Wannabe Drugs … of the Future
Ever have somebody copy you? You know, try to be like you? Imitate what you do, where you go? try to get what you have? They wannabe like you. Well, maybe not just exactly like you — kind of like you and better than you all at the same time. It’s happening with ketamine. We’ve been talking […]
IV Ketamine and Treatment-Resistant Mood Disorders
IV Ketamine and Treatment-Resistant Mood Disorders After reading today about a beautiful young man – let’s call him Tom – whose life ended tragically at the crossroads of despair, I started thinking. Like many of my own patients, he had a wondrously warm and giving heart — and a compassionate heart the size of Montana for […]
IV Ketamine: Doing What Prozac Can’t
Excitement about IV Ketamine Recently, I shared my perspective about the consensus statement released by the American Psychiatric Association’s Council of Research on Novel Biomarkers and Treatments Task Force. Their statement was about the use of IV ketamine for treating mood and other psychiatric disorders. That Task Force, in its consensus statement, assured members of the […]
Treatment-Resistant Depression Meets Its Match
Do you know someone who’s been listless and hopeless for a really long time? More than weeks or even months … someone who’s been taking antidepressants for years, and has never really felt better? Have you noticed how years of despair affects a person’s outlook so deeply that their personality seems to change? Clare’s story Take Clare. […]
JAMA Psychiatry Weighs In: The “Ketamine for Depression” Buzz
JAMA: “Ketamine for Depression” Buzz The mental health community is all a-buzz about IV ketamine for treating depression and other psychiatric disorders, and for good reason. For the first time, people who’ve been treated without success for years are experiencing relief and enjoying their lives. For anyone who has suffered from psychiatric disorders without relief […]
Ketamine IV, IM, or IN for Depression: Which is Best? (Does It Matter?)
Why do we always talk about IV ketamine for treatment-resistant depression, rather than just ketamine? Can’t we give it any old way…ketamine IV, IM, or IN for depression? Why is it so important that it be given as an intravenous infusion, rather than as an intramuscular injection or an intranasal spray? Ketamine IV, IM, or IN […]
How Ketamine Turbo Boosts Brain Compost to Improve Your Mood
In a recent post, we talked about the impact of Brain Derived Neurotrophic Factor (BDNF) on the prolific development of neuronal synapses, or nerve connections, in the brain. BDNF is like a rich, organic compost that spurs dense growth. And we talked about how IV ketamine turbo boosts brain compost and multiplies the connections in your […]
Why Some People Get PTSD…and Others Don’t
Ever notice how some people seem to collapse under an onslaught of traumatic experiences, and others almost seem to rise above them? Almost as if demonstrating their resilience? Why some people get PTSD and others don’t..that’s the question. People tend to say the latter type is “strong”… and the former type is weak…unable to withstand […]